Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp267 | Genetics | ECTS2013

A genetic determinant of vitamin D and its role in prostate cancer

Trummer Olivia , Thurner Eva , Langsenlehner Tanja , Langsenlehner Uwe , Krenn-Pilko Sabine , Marz Winfried , Pieber Thomas , Obermayer-Pietsch Barbara , Renner Wilfried

Preclinical and epidemiologic data suggest that vitamin D deficiency may play a role in the pathogenesis and progression of prostate cancer. Based on recently reported genetic determinants of vitamin D insufficiency we investigated a functional T>G single nucleotide polymorphism (SNP) in the group-specific component (GC) gene for its association with 25-hydroxy (25-OH) vitamin D and 1.25 dihydroxy (1.25-OH) vitamin D levels and further to test a possible association with m...